An Elusive Disease: Kicking Gastric Cancer in the Gut

By EndoPro Staff Helen Shipstad thought she had an ulcer. The woman from Derbyshire, England said in an interview with the Stomach Cancer Awareness Network, “I started getting heartburn, and burning, and just discomfort.” Those symptoms were appearing in February of 2021. When over-the-counter remedies didn’t help, she scheduled an appointment with a GI specialist. To Shipstad’s surprise, an endoscopy ...

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Too Much Belly Fat Hinders Digestive Disease Medications

The mass and composition of our bodies can significantly affect the way medications are metabolized and absorbed, according to recent research from Cedars-Sinai, in Los Angeloes, found that inflammatory bowel disease (IBD) patients with higher levels of intra-abdominal visceral adipose tissue—a distinctive type of fat inside the abdomen—had lower rates of remission when treated with certain anti-inflammatory medications. The findings ...

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Scientists Identify Genetic Variant Linked to Perianal Crohn’s Disease

Cedars-Sinai investigators have identified a genetic variant that increases people’s risk of developing perianal Crohn’s disease, the most debilitating manifestation of Crohn’s disease. The variant generates changes to DNA that lead to a loss of protein function, which in turn, alters how the body recognizes and handles bacteria, making it less effective at fighting infections. The discovery is published in ...

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Duodenoscopes With Disposable Caps Have Less Microbial Contamination

According to a study published in JAMA Internal Medicine, using duodenoscopes with disposable elevator caps during endoscopic retrograde cholangiopancreatography (ERCP) led to lower rates of contamination following high-level disinfection, compared to standard scope designs. The disposable caps did not alter the performance and safety of the procedure, the randomized ICECAP trial showed. The study, “Effect of Disposable Elevator Cap Duodenoscopes ...

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New Method Detects Gut Microbes That Activate Immune Cells

Cedars-Sinai investigators have developed a method to help identify which human gut microbes are most likely to contribute to a slew of inflammatory diseases like obesity, liver disease, inflammatory bowel disease, cancer and some neurological diseases. The technique, described in the peer-reviewed journal Science Translational Medicine, uses a protein found in blood that detects the gut microbes that have crossed ...

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