For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth had a much better chance of surviving treatment. When antibiotics hit a population of bacteria, often a small fraction of “persister” cells survive to pose a ...

A startling discovery published in the journal Science reveals how your past history of minor bacterial infections can add up with age to cause a severe inflammatory disease. Small bacterial infections that may go unnoticed and which the body easily clears without treatment, such as occurs during mild food poisoning, nevertheless can start a chain of events that leads to ...

Living in rural households decreases a person’s risk of developing inflammatory bowel disease (IBD), particularly for young children and adolescents, according to a new study by researchers at the Children’s Hospital of Eastern Ontario (CHEO) Research Institute, Institute for Clinical Evaluative Sciences (ICES), and the Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC). “Our findings show that children, particularly those under the age ...

Clinical trial recruitment is a challenging step toward FDA approval of new treatments for patients across all disease states; this is especially true for inflammatory bowel diseases (IBD). The Crohn’s & Colitis Foundation (the Foundation) launched today a dedicated Clinical Trials Community (the Community) for IBD. The Community is designed to educate patients, caregivers, and healthcare providers about the clinical ...

A new study has uncovered a link between being overweight or obese in adolescence and an increased risk of developing colon cancer in adulthood. Obesity was also associated with an elevated risk of developing rectal cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings come at a time of growing concern about the ...