New ‘jumping’ superbug gene discovered, resistant to last-resort antibiotic

While sifting through the bacterial genome of salmonella, Cornell University food scientists discovered mcr-9, a new stealthy, jumping gene so diabolical and robust that it resists one of the world’s few last-resort antibiotics. Doctors deploy the antibiotic colistin when all other infection-fighting options are exhausted. But resistance to colistin has emerged around the globe, threatening its efficacy. “This last-resort antibiotic ...

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Breaking open the gates of antibiotic resistance

Antibiotic resistance is a major health threat, with about two million people in the US getting an antibiotic-resistant infection per year, according to the Centers for Disease Control and Prevention (CDC). Gram negative bacteria, including types like E.coli and Salmonella, are often more difficult to kill because of their two-pronged defenses. They have two membranes rather than one, and also have numerous ...

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Right combination of diet and bacteria limits cancer progression

The diet of a person can have significant effects on the gut microbiome, i.e. the populations of microorganisms such as bacteria which live in the human gut. It is well recognized that dietary habits through complex metabolic interactions contribute to cancer prevention. More specifically, diets rich in fiber reduce the risk of developing specific cancers such as colorectal cancer. Although ...

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Fight Colorectal Cancer launches clinical trial finder mobile app in partnership with Flatiron Health

Fight Colorectal Cancer (Fight CRC) has collaborated with Flatiron Health to develop a smartphone application for its Late-Stage, MSS-CRC Clinical Trial Finder. The first-of-its-kind app — now available for both iOS and Android — enables patients with late-stage Microsatellite Stable (MSS) colorectal cancer to research relevant clinical trials via their phone. The Fight CRC Clinical Trial Finder was the work of stage IV colorectal cancer survivor, Dr. Tom Marsilje, who originally ...

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Scientists discover how ‘superbug’ E. coli clones take over human gut

A “superbug” clone of E. coli has evolved to prevent itself from becoming so dominant that it could potentially wipe out the bacteria from existence, scientists led by the University of Birmingham have discovered. The researchers investigated how and why a clone of E. coli called ST131 has become the major cause of drug-resistant E. coli infections, but not so dominant that ...

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