Gut reaction: Repeated food poisoning triggers chronic disease

A startling discovery published in the journal Science reveals how your past history of minor bacterial infections can add up with age to cause a severe inflammatory disease. Small bacterial infections that may go unnoticed and which the body easily clears without treatment, such as occurs during mild food poisoning, nevertheless can start a chain of events that leads to ...

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Molecule plays dual role in bowel health and disease

A molecule that controls intestinal cell growth plays a dual role maintaining gut health and promoting diseases such as cancer, says a study in eLife. The discovery in mice sheds light on the intricate mechanisms that control cell turnover in the gut, and provides a potential new therapeutic target for intestinal diseases such as bowel cancer. The lining of our ...

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‘Poop pill’ capsule research paves the way for simpler C. difficile treatment

An Alberta-led clinical trial has shown Fecal Microbiota Transplant (FMT) is effective in treating clostridium difficile (C. difficile) infections whether delivered by colonoscopy or by swallowing capsules. The finding, published in the Journal of the American Medical Association, could revolutionize and broaden the use of FMT, which restores the healthy balance of bacteria living in the intestine by transferring a ...

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Racial disparities persist in the survival of patients with ovarian, colon, and breast cancer

Three new articles present trends in survival for patients with ovarian, colon, and breast cancer in the United States by race and stage. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings reveal large, consistent, and persistent racial disparities in survival. For the analyses, a team led by investigators at the Centers for Disease ...

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Finding a less poopy solution for fecal transplant regulation

As fecal matter transplants (FMTs) continue to be more widely adopted, it is critical to have an appropriate regulatory framework in place, authors of this Policy Forum emphasize. They go on to outline key areas for improvement, compared to current regulatory approaches. The transfer of stool from one healthy donor to a recipient for re­current Clostridium difficile infection (CDI) is ...

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