Study establishes the first public collection of bacteria from the intestine of mice

Mouse models are extensively used in pharmaceutical and medical research, and it is known that the communities of microbes in their intestine can have a significant impact on the research output. However, there is still insufficient information available about many bacteria inhabiting the intestine of mice. For the first time, a collection of cultured bacterial strains provides comprehensive information on ...

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Discovery of a novel gene for hereditary colon cancer

The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. The large-scale appearance of polyps is often due to a hereditary cause; in this case the disease can occur in multiple family members. Under the leadership of human geneticists of the University Hospital Bonn, a team of researchers ...

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Fusobacteria use a special sugar-binding protein to bind to colon tumors

Boston, MA — Some bacteria, called fusobacteria, commonly found in the mouth, use a sugar-binding protein to stick to developing colorectal polyps and cancers, according to a new study by researchers from Harvard T.H. Chan School of Public Health and Hebrew University-Hadassah School of Dental Medicine. While certain fusobacteria have previously been shown to worsen colorectal cancer in animals by the ...

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‘Generic’ Biologic Drugs Appear Comparable to Brand-Name Counterparts

NEW ANALYSIS SUGGESTS COMMON AND COSTLY MEDICATIONS MADE FROM LIVING CELLS CAN BE EQUIVALENT EVEN WHEN MANUFACTURED BY DIFFERENT COMPANY Generic forms of a biologic drug used to treat rheumatoid arthritis, inflammatory bowel disease and psoriasis appear to be as safe and effective as their brand-name counterparts, a new Johns Hopkins Bloomberg School of Public Health analysis suggests. Biologics, or ...

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Higher weekly activity levels linked to lower risk of five

Daily activity levels need to be several times higher than recommended minimum Higher levels of total physical activity are strongly associated with lower risk of five common chronic diseases – breast and bowel cancer, diabetes, heart disease and stroke, finds a study in The BMJ today. Many studies have shown the health benefits of physical activity. This has led the ...

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