Molecule prevents effect of chemotherapy

Danish researchers from Aarhus University Hospital and Aarhus University are behind a possible breakthrough in the treatment of colorectal cancer. Annually about 2000 Danish patients with colorectal cancer are treated with chemotherapy. Today, a range of different chemotherapeutic regimens are available. However, deciding which regimen to use is not easy. Unfortunately, it is currently impossible to predict which regimen will ...

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Olympic stomach upsets — leaky gut symdrome?

A number of competitors at the Rio Olympics have reported stomach problems. Team GB officials have denied that athletes have fallen victim to food poisoning at the Olympic athletes’ village in Rio, despite a number complaining of upset stomachs. Professor Raymond Playford, a gastro-intestinal expert and Professor of Medicine from Plymouth University Peninsula Schools of Medicine and Dentistry, suggests that ...

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Natural compound from a deep-water marine sponge found to reduce pancreatic tumor size

Scientists at Florida Atlantic University’s Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale’s coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound. This work resulted in the award of a ...

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Ramucirumab in stomach cancer: Added benefit not proven

Former orphan drug is undergoing regular early benefit assessment / studies submitted were unsuitable Ramucirumab (trade name: Cyramza) is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours. This aims to slow the growth of the tumours. As a so-called orphan drug, i.e. a drug for the treatment ...

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First 3-D map of cell-building protein linked to cancer

Walter and Eliza Hall Institute researchers have revealed for the first time the three-dimensional molecular ‘map’ of a protein that has been pinpointed as a driver of many types of cancers. The unprecedented view of the protein doublecortin kinase like domain 1 (DCLK1) could provide clues to how it contributes to cancer formation and progression. DCLK1 is a protein that ...

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