News

Rare mutations in bowel cancer may identify patients with a better prognosis

An international collaboration between the University of Oxford and other European institutions has uncovered a correlation between a rare mutation in bowel cancers and a better prognosis, raising the possibility that patients with such tumours may not require chemotherapy after surgery. The study focused on colorectal (bowel) cancers and examined the presence of mutations in a gene that is essential ...

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VA and Regenstrief researchers working to identify risk factors for colon cancer under 50

While the incidence of colon cancer has been declining in individuals 50 years old and older in the United States, it is steadily rising in those under age 50. With funding from the U.S. Department of Veterans Affairs, Thomas F. Imperiale, M.D., a VA and Regenstrief Institute clinician-researcher, is developing and validating a model to predict risk for colon cancer ...

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Dietary compound linked to heart disease may be influenced by gut microbiome

In the last five years, some scientists have cautioned against eating eggs and meat because these foods generate a common dietary compound, trimethylamine N-oxide (TMAO), that research has suggested plays a role in heart disease. A Cornell study recently published online in the peer-reviewed journal Molecular Nutrition and Food Research reports new results that raise questions about whether circulating TMAO causes heart ...

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Study finds Hispanic men in California need more screening for colorectal cancer

Colorectal cancer incidence and mortality rates in California have decreased markedly for men and women in all major racial-ethnic groups since 1990, except for Hispanic men. Colorectal cancer rates for Hispanic men have remained relatively the same, a disparity that can be improved by greater screening, a study of colorectal cancer trends from the UC Davis Institute for Population Health ...

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Intestinal flora effects drug response

Intestinal flora has multiple influences on human health, but researchers have revealed that it is also likely to have an effect on the body’s response to drugs. Recent research from Kumamoto University in Japan strongly suggests that changes in the intestinal flora, caused by antibacterial and antibiotic drugs or individual differences between people, may have an effect on a person’s ...

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