Author Archives: EndoPro Admin

Natural compound from a deep-water marine sponge found to reduce pancreatic tumor size

Scientists at Florida Atlantic University’s Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale’s coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound. This work resulted in the award of a ...

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Ramucirumab in stomach cancer: Added benefit not proven

Former orphan drug is undergoing regular early benefit assessment / studies submitted were unsuitable Ramucirumab (trade name: Cyramza) is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours. This aims to slow the growth of the tumours. As a so-called orphan drug, i.e. a drug for the treatment ...

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First 3-D map of cell-building protein linked to cancer

Walter and Eliza Hall Institute researchers have revealed for the first time the three-dimensional molecular ‘map’ of a protein that has been pinpointed as a driver of many types of cancers. The unprecedented view of the protein doublecortin kinase like domain 1 (DCLK1) could provide clues to how it contributes to cancer formation and progression. DCLK1 is a protein that ...

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‘Born to be bad’ or ‘born to be benign’ — testing cells for esophageal cancer risk

Genetically analysing lesions in the food pipe could provide an early and accurate test for oesophageal cancer, according to research led by Queen Mary University of London (QMUL), Academic Medical Center in Amsterdam and Arizona State University. The study, published in Nature Communications, shows that some cells that are ‘born to be bad’ could be identified early on, preventing the need ...

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Ginger-derived nanoparticles may be good medicine for Crohn’s disease and ulcerative colitis,

A recent study by researchers at the Atlanta VA took them to a not-so-likely destination: local farmers markets. They went in search of fresh ginger root. Back at the lab, the scientists turned the ginger into what they are calling GDNPs, or ginger-derived nanoparticles. The process started simply enough, with your basic kitchen blender. But then it involved super-high-speed centrifuging ...

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